Dr. Smaldone received a Bachelors Degree in Chemical Engineering at New York University School of Engineering in 1969. In 1975, he completed a combined M.D., Ph.D. Program at New York University School of Medicine. His thesis was in pulmonary mechanics. Dr. Smaldone received his clinical training as an intern and resident in the medicine program at The University of Rochester, New York, Strong Memorial Hospital. Between 1977 and 1980 he completed fellowships in Pulmonary Medicine and Environmental Physiology at The Johns Hopkins University. In 1996 he became Division Head. He is actively involved in multiple projects utilizing aerosols directed towards the study of inflammatory airway disease, airway geometry and drug delivery. In addition to his research activities, Dr. Smaldone actively practices at University Hospital. He specializes in pulmonary and critical care medicine. He is also the founding editor of the Journal of Aerosol Medicine.